In the experimental setting human contact is both more frequent and more intimate than in observational research, and the issue therefore assumes even greater importance. The present paper discusses two experimental studies of wolf information processing, one of which was conducted with unsocialized animals and one of which was conducted with socialized animals, and examines the both the management and methodological consequences of these approaches.
Frank, H., Hasselbach, L.M., & Littleton, D.M. (1986). Socialized vs. unsocialized wolves (Canis lupus) in experimental research. In M.W. Fox & L.D. Mickley (Eds.), Advances in animal welfare science 1986/87 (pp. 33-49). Washington, DC: The Humane Society of the United States.