While the attention given to preventing, assessing, and alleviating pain in research animals has increased noticeably in recent decades, much remains to be done both in terms of implementing best practices and conducting studies to answer outstanding questions. In contrast, the attention to distress (particularly non-pain induced distress) has shown no comparable increase. There are many reasons for this discrepancy, including the conceptual untidiness of the distress concept, the paucity of pharmacological treatments for distress, and perceived lack of regulatory emphasis on distress. These are challenges that need to be addressed and overcome. This book is intended to help meet these and other challenges to effectively tackling distress and pain in research animals. The chapter, in particular, distills the various recommendations regarding recognition, assessment, measurement and alleviation of animal distress and pain throughout this book, in order to provide the reader with practical information in a succinct format.
Conlee, Kathleen; Stephens, Martin; and Rowan, Andrew N., "The Minimization of Research Animal Distress and Pain: Conclusions and Recommendations" (2009). LAB. 23.