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This article summarizes information from a survey of biomedical scientists, specifically pharmacologists and toxicologists, on the use of laboratory animals and the potential for replacing their use with alternative methods for the development and evaluation of pharmaceutical substances. The majority of those surveyed felt that the alternatives could supplement or complement animal tests, but not replace the tests altogether. However, most favored the use of nonsentient material in safety tests.


This paper is an edited version of a report published by the Federal Health Office in 1982, entitled Tierschutz und Tierexperiment- Durchfuhrung, Bewertung und Aussage von Tierversuchen und alternativen Verfahren, bga-Bericht/81, Dietrich Reimer Verlag, Berlin, 1981.